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. 2019 Apr 30;4(2):e00058-19. doi: 10.1128/mSystems.00058-19

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Copyright © 2019 Tripathi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Principal-coordinate analysis (PCoA) of the gut microbiome and metabolome in ApoE^−/− and Ldlr^−/− mouse models. (a and b) PCoA of the microbiome (16S rRNA sequencing) data using unweighted UniFrac distances. (c and d) PCoA of the metabolome (untargeted LC-MS/MS) data using Bray-Curtis distances. The ordination is visualized along the duration of treatment (starting at 10 weeks of age, with an interval of 0.5 week). Axis 1, principal coordinate 1; IHH, intermittent hypoxia and hypercapnia; HFD, high-fat diet.