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letter
. 2019 Apr-Jun;23(2):178. doi: 10.5935/1518-0557.20190022

Zika virus during controlled ovarian hyperstimulation

Beuy Joob 1,, Viroj Wiwanitkit 2
PMCID: PMC6501748  PMID: 31038293

Dear Editor, we read the publication on “Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes” with a great interest. Filho et al. (2019) noted that “This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes.” Indeed, the identification of the virus in follicular fluid has been mentioned for a long time (Washington et al., 2016; Taitson et al., 2017). In animal model, the existence of the virus in oocytes is already reported (Broughton et al., 2017). Therefore, the report by Filho et al. (2019) should not be the first report.

Footnotes

CONFLICT OF INTEREST

None

REFERENCES

  1. Broughton DE, Scheaffer S, Skaznik-Wikiel ME, Halabi J, Govero J, Caine M, Diamond M, Moley K. ZIKA virus exhibits tropism to the ovary and increases follicular apoptosis in a mouse model. Fertil Steril. 2017;108:e35 [Google Scholar]
  2. Filho EA, Fácio CL, Machado-Paula LA, Oliveira MA, Martinhago CD, Araújo LP, Araújo LFP. Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes. JBRA Assist Reprod. 2019 Jan 07; doi: 10.5935/1518-0557.20180081. [Epub ahead of print] [DOI] [PMC free article] [PubMed] [Google Scholar]
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