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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Histopathology. 2019 Apr 25;74(7):1088–1097. doi: 10.1111/his.13840

Table 2.

Radiological findings on HRCT, grouped by presence or absence of bronchiolocentric fibrosis, in the total cohort and in patients diagnosed with idiopathic pulmonary fibrosis.

Total cohort (n=252)
IPF cohort (n=215)
With BCF Without BCF P value With BCF Without BCF P value


Number with HRCT, n (%) 88 (91.7) 138 (88.5) 65 (90.3) 126 (88.1)


Pattern, n (%) 0.33 0.48
 UIP 18 (20.5) 40 (29.0) 15 (23.1) 39 (31.0)
 Possible UIP 27 (30.7) 36 (26.1) 22 (33.8) 35 (27.8)
 Inconsistent UIP 43 (48.9) 62 (44.9) 28 (43.1) 52 (41.3)


Inconsistent features, n (%)
 Upper or mid-lung predominance 5 (5.7) 14 (10.1) 0.33 3 (4.6) 10 (7.9) 0.55
 Peribronchovascular predominance 20 (22.7) 26 (18.8) 0.50 13 (20.0) 20 (15.9) 0.55
 Extensive ground glass abnormality 18 (20.5) 20 (14.5) 0.28 15 (23.1) 17 (13.5) 0.10
 Profuse micronodules 2 (2.3) 1 (0.7) 0.56 1 (1.5) 1 (0.8) 1.00
 Discrete cysts 4 (4.5) 9 (6.5) 0.77 3 (4.6) 9 (7.1) 0.75
 Diffuse mosaic attenuation/air-trapping 18 (20.5) 23 (16.7) 0.48 11 (16.9) 19 (15.1) 0.83
 Consolidation in bronchopulmonary segment(s)/lobe(s) 2 (2.3) 3 (2.2) 1.00 2 (3.1) 3 (2.4) 1.00

Abbreviation: HRCT, high-resolution computed tomography; UIP, usual interstitial pneumonia