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. Author manuscript; available in PMC: 2020 Apr 11.
Published in final edited form as: Chemistry. 2019 Feb 13;25(21):5337–5371. doi: 10.1002/chem.201805075

Figure 4.

Figure 4

Catalytic active site of AChE (S203, H447, E334), the oxyanion hole (G121, G122, A204), and cation-binding pocket (W86, E202) without ACh being bound (left) and with ACh (right).