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. 2019 Apr 23;92(17):e1992–e2004. doi: 10.1212/WNL.0000000000007367

Figure 3. Slower AR is correlated with thinner cortex in select motor speech ROIs.

Figure 3

Strength of correlations between articulation rate (AR) and supplementary motor and premotor area regions of interest (ROIs) is greater than with inferior frontal or motor cortex ROIs. (A) Pearson r values are shown per ROI, along with significant (p < 0.05) correlations. (B) Scatterplot showing relationship between AR and cortical thickness using pooled subgroup data for each ROI returning overall group significance. (C) Scatterplot showing relationship between AR and cortical thickness using separate subgroup (nonfluent variant primary progressive aphasia [nfvPPA], logopenic variant primary progressive aphasia [lvPPA], semantic variant primary progressive aphasia [svPPA]) data for each ROI returning overall group significance. For panels B and C, open dots denote individual data, solid lines show linear group/subgroup trend, and gray-shaded region show 95% confidence interval. dIFo = dorsal pars opercularis; dMC = dorsal motor cortex; LH = left hemisphere; mdPMC = middle dorsal premotor cortex; midMC = middle motor cortex; midPMC = middle premotor cortex; pdPMC = posterior dorsal premotor cortex; pIFs = posterior inferior frontal sulcus; SMA = supplementary motor area; vIFo = ventral pars opercularis; vMC = ventral motor cortex; vPMC = ventral premotor cortex. *p < 0.05, **p < 0.01. +p < 0.1.