Table III.

Body weight (alive) and selected organ weights of NSG mice following three intravenous injections of 2 × 10⁶ ABCB5⁺ MSCs/animal or vehicle without cells on day 1, 15 and 29.

	Vehicle	2 × 106 MSCs/animal
Males
Body weight (alive), g	n = 10	n = 10
Baseline	27.9 (1.34)	27.9 (0.94)
13 weeks	34.4 (1.52)	32.7 (0.69)*
Organ weight, g	n = 10	n = 9
Brain	0.4783 (0.0168)	0.4853 (0.0120)
Heart	0.1800 (0.0132)	0.1684 (0.0069)
Kidneys	0.5599 (0.0572)	0.5079 (0.0269)
Liver	1.9112 (0.1416)	1.6879 (0.0532)**
Spleen	0.0259 (0.0062)	0.0222 (0.0028)
Testes	0.2059 (0.0122)	0.2047 (0.0083)
Thymus	0.2059 (0.0122)	0.2047 (0.0083)
Females
Body weight, g	n = 10	n = 10
Baseline	21.8 (1.29)	22.1 (1.59)
13 weeks	26.6 (1.23)	26.9 (2.13)
Organ weight, g	n = 10	n = 10
Brain	0.4931 (0.0125)	0.4879 (0.0143)
Heart	0.1395 (0.0111)	0.1373 (0.0108)
Kidneys	0.3076 (0.0204)	0.3112 (0.0185)
Liver	1.3087 (0.0888)	1.2165 (0.1176)*
Ovaries	0.0212 (0.0043)	0.0210 (0.0044)
Spleen	0.0249 (0.0037)	0.0243 (0.0033)
Thymus	0.0086 (0.0028)	0.0069 (0.0030)

Animals were followed up for 13 weeks. Values are means (SD).

^*P < 0.05

^**P < 0.01 versus vehicle group, t-test on log-transformed data (body weight) or after adjustment for body weight (organ weights).