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Effects of curcumin analogues on total tissue myeloperoxidase (MPO) activity (mU) normalized to (A) wet weight (grams) of the tissue or (B) protein content (mg) in the sample. MPO enzyme activity was significantly decreased both by C142 and C150 Mannich curcuminoids. MPO activity was measured as described in Section 4.6 of Materials and Methods. Results are shown as mean ± S.E.M.; n = 8–11; * p < 0.05, ** p < 0.01, *** p < 0.001 pair-wise comparison with TNBS-treated group.
