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The effect of theobromine (TB) on locomotor activity and spontaneous alteration behavior in rats assessed by the Y-maze test. (A) Locomotor activity of TB-fed rats (TB rats) and control rats (CN rats). There were no significant differences between groups in both trials. (B) TB rats had a significantly higher number of alteration in both trials compared to CN rats. Values are the mean ± S.E.M. (n = 8 for each group). * p < 0.05, ** p < 0.01; significant difference between groups.
