TABLE 3.
Pancreatic Cyst | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case No. |
Age at Diagnosis, y |
Type of IPMN |
Clinical Characteristics | No. | Size, mm | Location | MPD Dilatation, mm | EUS/ERCP | CEA, ng/mL |
Change in Cysts/ Progression |
Current Status | Follow-up, mo |
Image |
1 | 69* | BD | Incidental finding, asymptomatic | 7 | 30 | Head | 3 | No | NA | NA | No follow-up since initial imaging | NA | Figure 3A |
2 | 58†‡ | BD | Incidental finding, asymptomatic Transplant |
2 | 20 | Head and tail | 3 | EUS—clear communication seen with MPD | NA | Increase | Alive—no complications | 124 | Figure 3B |
3 | 72§ | MD | Symptomatic, abdominal pain | NA | NA | NA | >10 | ERCP—thick mucus from widely patent MPD | NA | Increase | Deceased—IPMN-related SBO | 56 | Figure 3C and 3D |
4 | 60†‡ | BD | Incidental finding during biliary sepsis, asymptomatic | 8 | 5 | Head, body, and tail | 3 | No | NA | No change | Alive—no complications | 51 | Supplemental Figure 2 |
5 | 72† | BD | Incidental finding, asymptomatic | 2 | 11 | Body and tail | 3 | No | NA | Minimal increase | Alive—no complications | 27 | Supplemental Figure 3 |
6 | 47† | BD | Incidental finding, asymptomatic | 1 | 11 | Head | 2 | No | NA | No change | Alive—no complications | 12 | Supplemental Figure 4 |
7 | 70§ | BD | Incidental finding during biliary sepsis Transplant |
3 | 14 | Head and body | 3 | EUS—communi-cation with MPD | 315 | Decrease | Alive—no complications | 33 | Supplemental Figure 5 |
8 | 61* | BD | Incidental finding, asymptomatic Transplant |
1 | 21 | Head | 2 | EUS—irregular MPD with dilated branch ducts in tail | 2,400 | Increase | Deceased—unrelated to IPMN | 88 | Supplemental Figure 6 |
9 | 66* | MPD | Pancreatitis Transplant |
No image available pre-subtotal pancreatectomy | ERCP—outside hospital | NA | Resected | NA—total pancreatectomy | NA | NA | |||
10 | 75§ | MPD | Incidental finding, asymptomatic | 3 | 23 | Head and tail | 2 | EUS—clear communication with MPD | NA | NA | Deceased—unrelated to IPMN | 20 | Supplemental Figure 7 |
11 | 60* | MT | Abnormal LFTs Transplant |
1 | 40 | Head | 5 | ERCP—dilated side branches with mucus extruding from major and minor papilla | 1.9 | No change | Deceased—unrelated to IPMN | 112 | Supplemental Figure 8 |
12 | 64* | MT | Transplant | Numerous | 28 | Head and body | 8 | EUS—upstream pancreatic duct dilation, smaller cysts in pancreas tail | 40 | Increase | Alive—proceeded to Whipple procedure at outside hospital; severe dysplasia on histologic evaluation | NA | Supplemental Figure 9 |
Cysts and family history.
PKD1 mutation identified.
Patient in the ADPKD MRI cohort.
Cysts only as per Pei criteria.
BD indicates branch duct; CEA, carcinoembryonic antigen; ERCP, endoscopic retrograde cholangiopancreatography; EUS, endoscopic ultrasonography; IPMN, intraductal papillary mucinous neoplasm; LFT, liver function test; MD, main duct; MT, mixed type; NA, not available; SBO, small-bowel obstruction.