Skip to main content
. 2019 Jan 29;15(6):1082–1099. doi: 10.1080/15548627.2019.1569933

Figure 4.

Figure 4.

Muscle-specific inactivation of VCP leads to the accumulation of autophagic debris. (a) Co-immunofluorescence for LC3 (green) and SQSTM1 (red), in 6-week-old control or Myl1p-cre-vcp-/- mice. Merged images also contain DAPI nuclei staining (blue). Scale: 100 μm. (b) Immunofluorescence for LC3 (red) and DAPI-stained nuclei (blue) in ACTA1p-cre/Esr1-vcp-/- mice after 4 wk post tamoxifen injection for 5 d. Scale: 100 μm. (c) Electron micrograph images of the TA from Myl1p-cre-vcp-/- mice. Scale bars: 2 μm and 600 nm.