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. 2019 Mar 5;10(1):1–12. doi: 10.1080/21655979.2019.1586056

Figure 5.

Figure 5.

Effects of miR-485-5p and its inhibitor on the cell invasion ability in NCI-H446 and NCI-H1688 cells. Cell invasion ability of NCI-H446 and NCI-H1688 cells was determined by Transwell matrigel invasion assay. The number of cells invaded into the matrigel were quantified and expressed as mean ± SEM from three independent experiments. (a), Transwell matrigel invasion assay of NCI-H446 cells; NCI-H446 cells were transfected with miR-485-5p mimics, miR-485-5p inhibitor or their corresponding controls (mimics-NC, inhibitor-NC), respectively; (b), comparison of the number of invaded cells among the NCI-H446 cells transfected with miR-485-5p mimics, miR-485-5p inhibitor or their corresponding controls; (c), Transwell matrigel invasion assay of NCI-H1688 cells; NCI-H1688 cells were transfected with miR-485-5p mimics, miR-485-5p inhibitor or their corresponding controls (mimics-NC, inhibitor-NC), respectively; (d), comparison of the number of invaded cells among the NCI-H1688 cells transfected with miR-485-5p mimics, miR-485-5p inhibitor or their corresponding controls (n=3, *p<0.05, **p<0.01).