FIG 4.

Mapping of hits in the MAPK signaling pathway. Hits that affected RABV at 18 h (yellow) or 36 h (red) or both (orange) are indicated (see link on KEGG database). Displayed proteins correspond to identified genes as follows: NIK = MAP3K14, MEK1 = MAP2K1, RSK2 = RPS6KA2, PTP = PTPN7/9, MKP = DUSP5/7/9, MLK3 = MAP3K11, MKK7 = MAP2K7, PP2CA = PPM1A, and MSK1/2 = RPS6KA5. Hits were retrospectively marked as validated (*) or OTE (#). (Reprinted from KEGG Pathway Maps with permission of the publisher.)