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. Author manuscript; available in PMC: 2019 May 25.
Published in final edited form as: Oncogene. 2016 Sep 19;36(10):1430–1439. doi: 10.1038/onc.2016.311

Figure 5. INO80 occupies genomic regions near lung cancer-associated genes.

Figure 5.

(A) Genome browser tracks and ChIP-qPCR validations showing Ino80 occupancy near selected lung cancer genes MAP3K1, CXCL5, SEC62, ZNF703, CTNNB1 in A549 cells. Two genomic regions near each gene were selected for the ChIP-qPCR validations: P1 corresponds to a region that is not bound by Ino80 based on ChIP-Seq, while P2 corresponds to a region that is bound by Ino80. (B) IPA showing the enrichment of cancer-associated genes in Ino80-bound genes. Selected top categories are shown, and please see Table S4 for the complete list. (C) Venn diagram showing the overlap between DEGs after Ino80 KD and Ino80-bound genes. (D) IPA of the 580 Ino80 target genes. Selected top categories are shown, and please see Table S5 for the complete list.