ABSTRACT
Plants of arum family are beautiful and attractive but, at the same time, they are poisonous. The toxic effects are due to calcium oxalate crystals. The toxicity ranges from minor oral cavity edema to lethal airway obstruction.
How to cite this article: Jadhav DR, Gugloth R. Poisoning due to Arisaema triphyllum Ingestion. Indian J Crit Care Med 2019;23(5):242–243.
Keywords: Airway compromise, Arisaema triphyllum, Hypersalivation
INTRODUCTION
Oxalate containing plants are widely present as different species like Anthurium (Anthurium species) Arum, Araceae (Arisaema species), Caladium (Caladium bicolor), Calla lily (Zantedeschia species), Chinese evergreen (Aglaonema species), Dieffenbachia etc.1
Calcium oxalate containing plants like Dieffenbachia are known for their irritant properties since last 200 years. They were used to treat gout, impotence, and its frigidity was also used to punish slaves. Today, they are admired for their ornamental beauty, so they are present in abundance at public places.2 We are presenting a case of Arisaema triphyllum poisoning with oral cavity and airway edema.
CASE REPORT
A 4-year-old child was brought to emergency department (ED) with complaints of excessive salivation and inability to speak since 2 hours after consuming roots of unknown plant while playing in the garden. He also had pricking sensation in throat, chest discomfort, and shortness of breath. There was no history of vomiting and abdominal pain. General physical examination revealed the pulse rate of 92 beats per minute, blood pressure of 114/76 mm Hg, SPO2 of 96% on room air, and respiratory rate (RR) of 18 breaths per minute. Examination of oral cavity showed excessive salivation, congestion of posterior pharyngeal wall, and swelling of uvula. Respiratory system examination revealed conducted sounds while other systemic examinations were normal. The diagnosis of Arisaema triphyllum ingestion was confirmed after child has identified the plant brought by his father. The child was treated with IV fluids, intramuscular injection adrenaline 0.3 mL (1:1000 dilution) for possible airway edema and obstruction. Pain relief was obtained initially with cold water and later with tablet paracetamol. Patient was continuously monitored for possible worsening due to airway compromise. After 24 hours of observation, patient was discharged.
DISCUSSION
Arisaema triphyllum, also known as jack in the pulpit, Indian turnip, bog onion, and brown dragon, belongs to family Aracea or Arums.3 The toxicity of Arisaema triphyllum is due to calcium oxalate crystals, which are mainly present in stem, leaves, and roots. The roots are considered as the most toxic part.4
Calcium oxalates are needle-like crystals, which when ingested, may pierce the mouth, throat, and digestive tract as they pass through and cause an intense discomfort, produce pain and edema. It also affects conjunctiva and skin when it comes in contact. Edema primarily is due to direct trauma from the needle-like crystals but bradykinins also play some role in edema formation.5,6
Majority of cases are among children younger than five years. Most cases are self-limiting, and morbidity and mortality is rare. But small dose of oxalate toxin is enough to cause intense sensations of burning in the mouth and throat, swelling, hypersalivation, and choking. The airway edema and obstruction can possibly be lethal.
There is no diagnostic test to confirm diagnosis. Only high index of suspicion and clear history of ingestion often gives clue for diagnosis. Treatment is often symptomatic in most of the cases, but emergency physician must be aware of potentially threatening airway and should prepare for it. One case of infant fatality is reported due to obstructed airway after ingestion of Dieffenbachia plant and another child death is reported due to vagotonia attributed to esophageal lesion caused by ingestion of philodendron leaves (Fig. 1), which contains calcium oxalate as a principle toxin similar to Arisaema triphyllum.7,8
Fig. 1.
Philodendron leaves
CONCLUSION
Though arum poisoning is self-limiting most of the time, it can be lethal so emergency physician should always be ready for difficult airway.
Footnotes
Source of support: Nil
Conflict of interest: None
REFERENCES
- 1.Beasley V. Plants of the Araceae family (plants containing oxalate crystals and histamine releasers). Vet Hum Toxicol. 1999;;899::A2639.. [Google Scholar]
- 2.Wang B,, Han L,, Chen C,, Wang Z. The complete chloroplast genome sequence of Dieffenbachia seguine (Araceae). Mitochondrial DNA A DNA Mapp Seq Anal. 2016;;27((4):):2913-–2914.. doi: 10.3109/19401736.2015.1060436. doi: 10.3109/19401736.2015.1060436. [DOI] [PubMed] [Google Scholar]
- 3.Araceae of North America Update, database (version 2010) Retrieved [nov 28 2017], from the Integrated Taxonomic Information System on-line database, http://www.itis.gov. [Google Scholar]
- 4.Graeme KA. Toxic plant ingestions. In: Auerbach PS,, editor. Wilderness Medicine. 6th ed. Philadelphia, PA:: Elsevier Mosby;; 2012.. [Google Scholar]
- 5.Lin TJ,, Hung DZ,, Hu WH,, Yang DY,, Wu TC,, Deng JF. Calcium oxalate is the main toxic component in clinical presentations of Alocasis macrorrhiza (L) Schott and Endl poisonings. Vet Hum Toxicol. 1998;;40((2):):93-–95.. [PubMed] [Google Scholar]
- 6.Zhong LY,, Wu H. Current researching situation of mucosal irritant compontents in Araceae family plants. Zhongguo Zhong Yao Za Zhi. 2006;;31((18):):1561-–1563.. [PubMed] [Google Scholar]
- 7.Bronstein AC,, Spyker DA,, Cantilena LR, Jr,, Green JL,, Rumack BH,, Giffin SL. 2009 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 27th Annual Report. Clin Toxicol (Phila). 2010;;48((10):):979-–1178.. doi: 10.3109/15563650.2010.543906. doi: 10.3109/15563650.2010.543906. [DOI] [PubMed] [Google Scholar]
- 8.McIntire MS,, Guest JR,, Porterfield JF. Philodendron–an infant death. J Toxicol Clin Toxicol. 1990;;28((2):):177-–183.. doi: 10.3109/15563659008993490. [DOI] [PubMed] [Google Scholar]