Dong-Hyun Youn
Dong-Hyun Youn
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,
Jinbong Park
Jinbong Park
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,
Hye-Lin Kim
Hye-Lin Kim
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
1,
Yunu Jung
Yunu Jung
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,
JongWook Kang
JongWook Kang
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,
Seona Lim
Seona Lim
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,
Gahee Song
Gahee Song
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,
Hyun Jeong Kwak
Hyun Jeong Kwak
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
1,
Jae-Young Um
Jae-Young Um
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
1,2,*
1Department of Pharmacology and Basic Research Laboratory for Comorbidity Regulation, College of Korean Medicine, Kyung Hee University, Seoul, South Korea
2Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
Edited and reviewed by: Salvatore Salomone, Università degli Studi di Catania, Italy
✉*Correspondence: Jae-Young Um jyum@khu.ac.kr
This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology
Received 2019 Mar 28; Accepted 2019 Apr 30; Collection date 2019.
Keywords: berberine, benign prostatic hyperplasia, 5 alpha reductase, androgen receptor, mitogen-activated protein kinase, extracellular signal-regulated kinase
Copyright © 2019 Youn, Park, Kim, Jung, Kang, Lim, Song, Kwak and Um.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.