Table 3.
Preliminary anti-microbial activity for compounds 2, 6–8, 12.
| Microorganism | 2 | 6 | 7 | 8 | 12 | ST. (30 µg/mL) |
|---|---|---|---|---|---|---|
| Fungi | Amphotericin B | |||||
| Aspergillus niger | 18.8 ± 0.63 | 19.3 ± 0.63 | 18.4 ± 1.20 | 19.2 ± 0.72 | 23.3 ± 0.72 | 23.3 ± 0.58 |
| Geotricum candidum | 19.3 ± 0.58 | 18.1 ± 0.58 | 16.3 ± 0.63 | 17.3 ± 0.72 | 22.3 ± 1.20 | 25.2 ± 0.72 |
| G(+) Bacteria | Ampicillin | |||||
| Staphylococcus aureus | 17.6 ± 0.85 | 19.3 ± 0.58 | 21.1 ± 0.63 | 13.5 ± 1.20 | 20.1 ± 0.58 | 23.7 ± 0.63 |
| Staphylococcus epidermidis | 18.1 ± 1.20 | 17.4 ± 0.58 | 20.7 ± 0.72 | 15.3 ± 0.44 | 17.6 ± 0.72 | 22.4 ± 0.3 |
| Bacillis subtilis | 18.3 ± 0.63 | 22.7 ± 1.20 | 20.1 ± 0.53 | 18.2 ± 0.58 | 24.3 ± 0.58 | 32.4 ± 1.20 |
| Streptococcus pyogenes | NA | NA | NA | NA | NA | 24.5 ± 0.63 |
| G(−) Bacteria | Gentamicin | |||||
| Pseudomonas aeruginosa | NA | NA | NA | NA | NA | 22.3 ± 0.58 |
| Escherichia coli | 20.2 ± 0.58 | 20.3 ± 0.63 | 19.3 ± 1.20 | 19.3 ± 0.63 | 23.7 ± 0.72 | 25.4 ± 1.20 |
| Klebsiella pneumoniae | 18.2 ± 1.20 | 18.2 ± 0.58 | 19.2 ± 1.20 | 16.3 ± 0.63 | 19.3 ± 0.63 | 22.6 ± 0.63 |
| Salmonella typhimurium | 17.5 ± 0.63 | 20.4 ± 0.72 | 18.4 ± 0.58 | 19.3 ± 0.58 | 21.6 ± 0.63 | 23.3 ± 0.58 |
The tested compound has activity similar to reference drug.