Table 6.
Preliminary anti-microbial activity for compounds 21b, 24 and 25.
| Microorganism | 21b | 24 | 25 | ST. (30 µg/mL) |
|---|---|---|---|---|
| Fungi | Amphotericin B | |||
| Aspergillus niger | 19.2 ± 0.72 | 26.3 ± 0.63 | 23.3 ± 0.72 | 23.3 ± 0.58 |
| Geotricum candidum | 16.3 ± 0.72 | 24.2 ± 0.63 | 21.4 ± 0.72 | 25.2 ± 0.72 |
| G(+) Bacteria | Ampicillin | |||
| Staphylococcus aureus | 17.5 ± 1.20 | 22.7 ± 1.20 | 20.3 ± 0.43 | 23.7 ± 0.63 |
| Staphylococcus epidermidis | 21.3 ± 0.44 | 21.3 ± 0.58 | 19.8 ± 0.58 | 22.4 ± 0.3 |
| Bacillis subtilis | 18.2 ± 0.58 | 28.9 ± 0.72 | 25.4 ± 0.53 | 32.4 ± 1.20 |
| Streptococcus pyogenes | NA | NA | NA | 24.5 ± 0.63 |
| G (−) Bacteria | Gentamicin | |||
| Pseudomonas aeruginosa | NA | NA | NA | 22.3 ± 0.58 |
| Escherichia coli | 20.3 ± 0.63 | 25.6 ± 1.20 | 24.3 ± 0.53 | 25.4 ± 1.20 |
| Klebsiella pneumoniae | 21.3 ± 0.63 | 23.8 ± 1.20 | 21.5 ± 0.53 | 22.6 ± 0.63 |
| Salmonella typhimurium | 19.9 ± 0.58 | 25.4 ± 0.72 | 22.6 ± 0.63 | 23.3 ± 0.58 |
The tested compound has activity exceed the reference drug.
The tested compound has activity similar to reference drug.