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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Bone. 2019 Apr 24;124:89–102. doi: 10.1016/j.bone.2019.04.012

Figure 5. Short-term AZ treatment decreases bone mass accrual, but not bone architecture in young or old mice.

Figure 5.

A) BMD of young and middle-aged mice following veh- or AZ-treatment (n=8–10). Cancellous microarchitecture evaluated by μCT in the B) L4 vertebra and C) distal femur (n=8–9). Representative images are shown. D) Cortical bone geometry evaluated by μCT in the femoral mid-diaphysis (n=8–9). Representative images are shown. Bars represent mean±SD, black line: p<0.05, for the overall age effect and *p<0.05, vs veh-treated mice at the same age by two-way ANOVA, Tukey.