Table 1 –

Patient demographics and characteristics relative to seizure outcomes. Reported are p-values for the univariate analysis between each variable and seizure outcome. Significant values (p<0.05) are denoted by bold font.

	Entire Cohort		Association with Engel I outcome				Association with Engel I or II outcome
	n = 234		p-value				p-value
	μ ± σ	range	6 months	12 months	18 months	24 months	6 months	12 months	18 months	24 months
Age [years]	42 ± 15	(7 – 82)	0.005	0.213	0.477	0.652	0.020	0.001	0.053	0.093
Follow-up[months]	30 ± 14	(12 – 75)
	n	%
Gender
Female	124	53.0%	0.984	0.636	0.185	0.534	0.340	0.210	0.729	0.643
Handedness†
Right	161	83.4%
Left	29	15.0%	0.533	0.218	0.324	0.438	0.611	0.656	0.929	0.679
Ambidextrous	3	1.6%
Side of LITT
Left	136	58.1%	0.604	0.732	0.719	0.953	0.804	0.691	0.690	0.440
rHS on MRI
Yes	172	73.5%	0.048	0.289	0.225	0.613	0.232	0.587	0.751	0.969
Dual Pathology on MRI†
Yes	49	21.1%	0.504	0.454	0.043	0.171	0.322	0.933	0.206	0.537
PET†
Ipsilateral	139	73.5%	0.749	0.423	0.140	0.262	0.879	0.670	0.660	0.924
Negative	29	15.3%
Bilateral	16	8.5%
Contralateral	3	1.6%
Seizure Type*
FIAS	223	95.3%	0.311	0.392	0.506	0.158	0.800	0.701	0.369	1.000
FTC	107	45.7%	0.841	0.506	0.490	0.106	0.016	0.007	0.109	0.030
FAS	38	16.2%	0.684	0.708	0.327	0.870	0.206	0.074	0.078	0.346
EEG Localization†
Ipsilateral Temporal	180	83.7%	0.427	0.175	0.302	0.069	0.630	0.379	0.551	0.618
Bitemporal	20	9.3%
Multifocal	5	2.3%
Non-localized	6	2.8%
Ipsilateral Extratemporal	3	1.4%
Contralateral Temporal	1	0.5%
Invasive Monitoring
Yes	48	20.5%	0.978	0.959	0.475	0.942	0.749	0.696	0.564	0.950

^(*)Since patients may have more than one seizure types, each patient could belong to multiple seizure type categories. For this reason, the total percentage of patients for this variable is greater than 100%.

^(†)Variables with missing data. The numbers and percentages reported reflect the number of patients missing data.