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. 2019 Jun 4;21(7):721–729. doi: 10.1016/j.neo.2019.04.009

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© 2019 Published by Elsevier Inc. on behalf of Neoplasia Press, Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

(A) All genes on chromosome 13 (log2 ratio) are plotted consecutively for each DLD-1 + 13 clone (x-axis), with each diamond representing one gene. The highest up-regulated group of genes, which belong to the contiguous locus on 13q13.3 are color-coded red. The second up-regulated group of genes on 13q32.1 is color-coded green. RASL11A, the most down-regulated gene on chromosome 13, is color-coded blue. The red line depicts the zero line. Genes on chromosome 16 are plotted at the right for comparison. (B) Correlation plot between the RASL11A gene expression levels (log2 ratio, x-axis) and the RASL11A protein expression levels (average ratio, y-axis) for all eight DLD-1 + 13 clones.