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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Toxicon. 2019 Apr 20;165:22–30. doi: 10.1016/j.toxicon.2019.04.006

Figure 4.

Figure 4.

Quantification of an in vivo permeability assay was performed using the modified Miles assay. Mice were injected intravenously with 100 μL of Evans blue dye, followed immediately by a subcutaneous injection of saline, Hellerin (172 ng, 70 nM), or VEGF-A (143 ng, 50 nM). The results are presented as nanograms of weight of extravasated Evans blue dye per milligram of weight of tissue sample. * P<0.05, compared with saline control.