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. 2019 May 25;7(5):148. doi: 10.3390/microorganisms7050148

Figure 3.

Figure 3

TB infection cycle indicates intracellular changes of the bacilli during the different stages of the infection. The first adaptations occur during phagocytosis of the bacilli by the macrophages. The inner environment of the macrophages starts changing, which causes further adaptations of the bacilli and can include the switch to dormant bacilli. The last adaptation includes the resuscitation from dormant to active bacilli and the changes during airborne transmission.