“Exotic” forms of Vav proteins found in invertebrate species.Depiction of the structure of Vav proteins in the indicated organisms (Uniprot accession codes are indicated for each protein). MRP-S33, mitochondrial ribosomal protein S33; Tm, transmembrane domain; CLECT, C-type lectin or carbohydrate-recognition domain; KR, kringle domain; LIM, zinc-binding domain present in Lin-11, Isl-1, and Mec-3; HOX, homeobox; EHN, epoxide hydrolase N-terminus; ABHD1, abhydrolase domain-containing 1. Please note that the relevance of the “exotic” version detected in Trichuris suis is still unclear since there is discrepancy in the overall structure of the locus in three independent animals of this species that have been sequenced. In the rest of species, they do seem to represent bona-fide loci.