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The Cochrane Database of Systematic Reviews logoLink to The Cochrane Database of Systematic Reviews
. 2011 Mar 16;2011(3):CD005452. doi: 10.1002/14651858.CD005452.pub2

Gabapentin for acute and chronic pain

Philip J Wiffen 1,, Henry J McQuay 2, Jayne Edwards 3, R Andrew Moore 4
Editor: Cochrane Pain, Palliative and Supportive Care Group
PMCID: PMC6564088  PMID: 21412888

Reason for withdrawal from publication

This review was withdrawn as it had been split in to two reviews on agreement with the Editor in Chief and the data was now considered to be out of date. The two new reviews which replace this piece of work can be found on The Cochrane Library as: 'Single‐dose oral gabapentin for established acute postoperative pain' and 'Gabapentin for 'Gabapentin for chronic neuropathic pain in adults'. The remaining gaps from the original review will be updated as soon as possible.

The editorial group responsible for this previously published document have withdrawn it from publication.

What's new

Date Event Description
10 June 2019 Amended Contact details updated.

History

Review first published: Issue 3, 2005

Date Event Description
16 February 2011 New search has been performed This review was withdrawn as it had been split in to two reviews on agreement with the Editor in Chief and the data was now considered to be out of date. The two new reviews which replace this piece of work can be found on The Cochrane Library as: 'Single‐dose oral gabapentin for established acute postoperative pain' and 'Gabapentin for 'Gabapentin for chronic neuropathic pain in adults'. The remaining gaps from the original review will be updated as soon as possible.
4 July 2010 Amended Jayne Rees reverted to maiden name Edwards so Cochrane Library citations of her Cochrane reviews would match the citations in Medline and other bibliographic databases
9 November 2009 Amended Contact details updated.
13 May 2009 Amended Contact details updated.
13 February 2009 Amended The authors are aware of unpublished trial data for Gabapentin which could affect the results of this review. This information together with that from trials published since 2005, will be considered when this review is updated in 2009.
7 November 2008 Amended Note added regarding unpublished data and statement added to declarations of interest section.
2 July 2008 Amended Converted to new review format.
23 August 2006 Amended New studies found but not yet included or excluded.
17 May 2005 New search has been performed This review was originally published as 'Anticonvulsant drugs for acute and chronic pain' (Wiffen 2000). At the third update in 2003, 12 new included studies were identified mainly of the newer anticonvulsants gabapentin and lamotrigine. In total the included studies provided data on six different chemical entities used in at least six identified neuropathic pain conditions. Issues of dose response and trial design added to the complexity. A decision was therefore taken to split this review into a number of smaller reviews each covering one chemical entity. This review describes studies examining the role of gabapentin in acute and chronic pain.

Sources of support

Internal sources

  • Pain Research Funds, UK.

External sources

  • No sources of support supplied

Withdrawn from publication for reasons stated in the review


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