Table 4.
Fatty acid composition of liver phospholipids.
| CTRL | HF | HF-Phaeo | ||||
|---|---|---|---|---|---|---|
| Fatty Acid (mol %) | Mean | SD | Mean | SD | Mean | SD |
| SFA | ||||||
| 14:0 | 0.18 | 0.05 | 0.41 *** | 0.05 | 0.32 ***† | 0.04 |
| 16:0 | 20.94 | 1.08 | 18.91 * | 1.48 | 18.45 * | 1.16 |
| 18:0 | 17.41 | 2.21 | 19.58 | 1.01 | 21.95 * | 2.47 |
| Total SFA | 38.53 | 1.83 | 38.90 | 1.74 | 40.72 | 1.55 |
| MUFA | ||||||
| 16:1 | 1.09 | 0.39 | 0.84 | 0.19 | 0.78 | 0.23 |
| 18:1(n-7 + n-9) | 7.74 | 1.43 | 9.42 * | 0.68 | 7.29 † | 0.72 |
| 20:1n-9 | 0.22 | 0.06 | 0.14 | 0.07 | 0.12 * | 0.06 |
| 22:1 | 0.26 | 0.05 | 0.39 | 0.10 | 0.20 † | 0.16 |
| 24:1n-9 | ND | - | ND | - | ND | - |
| Total MUFA | 9.27 | 1.88 | 10.72 | 0.99 | 8.38 † | 1.02 |
| PUFA | ||||||
| 18:2n-6 | 11.15 | 1.08 | 7.76 ** | 1.49 | 7.89 ** | 1.12 |
| 20:2n-6 | ND | - | ND | - | ND | - |
| 20:4n-6 | 28.07 | 2.29 | 26.44 | 2.04 | 24.16 * | 1.38 |
| n-6 PUFA | 39.22 | 2.06 | 34.21 *** | 1.47 | 32.05 *** | 1.65 |
| 18:3n-3 | ND | - | ND | - | ND | - |
| 20:5n-3 | 0.19 | 0.05 | 0.42 | 0.10 | 2.29 ***† | 0.23 |
| 22:5n-3 | 0.90 | 0.11 | 0.98 | 0.17 | 2.43 ***† | 0.28 |
| 22:6n-3 | 8.78 | 1.11 | 10.00 | 1.01 | 9.99 | 0.72 |
| n-3 PUFA | 9.88 | 1.25 | 11.31 | 0.82 | 14.72 ***† | 1.03 |
| n-6 PUFA/n-3 PUFA | 4.04 | 0.72 | 3.04 *** | 0.28 | 2.19 ***† | 0.25 |
| Total PUFA | 49.10 | 1.17 | 45.52 ** | 1.46 | 46.76 ** | 1.09 |
| MUFA/SFA | 0.24 | 0.06 | 0.28 | 0.04 | 0.21 † | 0.03 |
| Δ9-Desaturase index ‡ | 0.31 | 0.07 | 0.32 | 0.02 | 0.25 † | 0.04 |
CTRL, standard diet; HF, high-fat diet; HF-Phaeo, high-fat diet supplemented with 12% of P. tricornutum; MUFA, mono-unsaturated fatty acids; ND, not detected; PUFA, polyunsaturated fatty acids; SFA, saturated fatty acids. Results are represented as mean values ± SD, n = 6. Mean values were significantly different from those of the CTRL group: * p < 0.05; ** p < 0.001; *** p < 0.0001 (one-way ANOVA; LSD post hoc test). † Significant difference compared with the HF group (p < 0.05). ‡ Δ9-Desaturase index = [18:1(n-7 + n-9)/ 18:0 + 18:1(n-7 + n-9)].