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The Journal of Neuroscience logoLink to The Journal of Neuroscience
. 1988 Dec 1;8(12):4440–4444. doi: 10.1523/JNEUROSCI.08-12-04440.1988

Conditional discrimination learning in Aplysia californica

RM Colwill 1, RA Absher 1, ML Roberts 1
PMCID: PMC6569555  PMID: 3199184

Abstract

Two experiments examined whether the relation between a conditioned stimulus (CS) and an unconditioned stimulus (US) might be brought under the control of contextual stimuli in the invertebrate Aplysia californica. Subjects received exposure to 2 different contexts. In both experiments, a tactile CS was paired with a shock US in one of those contexts. In the other context, that tactile CS was either nonreinforced (Experiment 1) or explicitly unpaired with the shock US (Experiment 2). Responding to the CS during a subsequent test was greater in the context in which that CS had been paired with the US compared with the context in which it had been nonreinforced or unpaired. These findings are discussed in terms of theories of conditional discrimination learning.


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