Table 4.
Functional enrichment analysis representing the top 10 GO terms and pathways of DEGs in the NSCLC group. Enriched terms were ranked based on the BH-adjusted p-value.
| GO ID | GO term | No. of Genes | BH-p-value |
|---|---|---|---|
| Biological Processes | |||
| GO:0051301 | Cell division | 55 | 3.55E-13 |
| GO:0007067 | Mitotic nuclear division | 42 | 1.28E-10 |
| GO:0052697 | Xenobiotic glucuronidation | 9 | 1.01E-07 |
| Molecular Functions | |||
| GO:0005515 | Protein binding | 459 | 6.17E-10 |
| GO:0044822 | Poly(A) RNA binding | 87 | 1.49E-05 |
| GO:0005178 | Integrin binding | 19 | 9.27E-05 |
| Cellular Components | |||
| GO:0070062 | Extracellular exosome | 215 | 5.72E-18 |
| GO:0005654 | Nucleoplasm | 188 | 7.68E-10 |
| GO:0005615 |
Extracellular space |
108 |
6.86E-09 |
| KEGG ID |
KEGG pathway |
No. of Genes |
BH-p-value |
| hsa00053 | Ascorbate and aldarate metabolism | 11 | 1.25E-04 |
| hsa00982 | Drug metabolism – cytochrome P450 | 16 | 1.92E-04 |
| hsa00040 | Pentose and glucuronate interconversions | 11 | 8.21E-04 |
| hsa05150 | Staphylococcus aureus infection | 13 | 9.92E-04 |
| hsa04110 | Cell cycle | 20 | 9.99E-04 |