Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hydrazine and aliphatic (or alicyclic) primary and secondary amines attack purine 8,2′-O-cyclonucleosides at C-8 to give the corresponding 8-substituted purine arabinoside derivatives in good yields. Oxidation of the appropriate 8-hydrazinopurine arabinosides with yellow mercury (II) oxide gives ara-A, ara-Hx and ara-G in high yields.
