Abstract
The syntheses of some thymidine analogues, including 2′-deoxy-5-ethynyluridine and E-5-(2-bromovinyl)-2′-deoxyuridine are outlined. Some of these compounds show significant anti-herpes activity invitro.
. 1978;5(Suppl 1):s103–s108. doi: 10.1093/nar/1.suppl_1.s103
The synthesis and properties of some antiviral nucleosides
RT Walker
*, PJ Barr
*, EDe Clereq
+, J Descamps
+, AS Jones
*, P Serafinowski
*
RT Walker
*Department of Chemistry, University of Birmingham, Birmingham B15 2TT, UK
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PJ Barr
*Department of Chemistry, University of Birmingham, Birmingham B15 2TT, UK
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EDe Clereq
+Rega Instituut Katholieke Universiteit, B-3000 Leuven, Belgium
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J Descamps
+Rega Instituut Katholieke Universiteit, B-3000 Leuven, Belgium
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AS Jones
*Department of Chemistry, University of Birmingham, Birmingham B15 2TT, UK
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P Serafinowski
*Department of Chemistry, University of Birmingham, Birmingham B15 2TT, UK
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*Department of Chemistry, University of Birmingham, Birmingham B15 2TT, UK
+Rega Instituut Katholieke Universiteit, B-3000 Leuven, Belgium
Issue date 1978 Jan 1.
© 1978 Information Retrieval Limited
PMCID: PMC6581330