Figure 4.

High SUC ¹³C polarization >10 % was achieved using SAMBADENA and T‐GM (Figure 1). Non‐localized ¹³C MR spectra of hyperpolarized SUC (176 ppm) and a thermally polarized acetone reference at natural abundance (210 ppm) were acquired at 7 T. For SAMBADENA, ¹H decoupling was applied during t_bypass and data acquisition (t _MLEV,90°=700 μs). With respect to the thermal reference, the maximal observed polarization was quantified to 11.9 %, corresponding to a signal enhancement at 7 T of ≈20.000. Experimental details: setup 2, E4.