Table 2.

T3SS and T6SS effectors in E. piscicida EIB202.

#	Protein name or tag #	T3SS or T6SS effector	Function	Location	Reference
1	ETAE_0866, EseG	T3SS	Interact with α-tubulin and disassemble microtubule	Membrane	[23,34,71,72]
2	ETAE_0888, EseJ	T3SS	Inhibit adhesion and promote intracellular replication, decrease ROS production		[32,71,72]
3	ETAE_1586, EseK	T3SS	Inhibit MAPK activation, promote colonization in zebrafish larvae		[24,71,72]
4	ETAE_1604	T3SS	Hypothetical protein		[72]
5	ETAE_1757, EseH/EseN*	T3SS	Phosphothreonine lyase, inhibit MAPK signalling pathway	Nucleus	[71,72,84]
6	ETAE_2186, Trxlp	T3SS	Thioredoxin-like, promote inflammasome NLRC4 activation		[72,73]
7	ETAE_2188	T3SS	Hypothetical protein		[72]
8	ETAE_3282	T3SS	Hypothetical protein		[72]
9	ETAE_1303, EseL	T6SS	Major cold shock protein?		[71]
10	ETAE_2316, EseM	T6SS	Major cold shock protein?		[71]
11	ETAE_2428, EvpP	T6SS	Prevent NLRP3 inflammasome activation, promote colonization in mice	Membrane	[71,77]
12	ETAE_2438, EvpJ	T6SS	Hypothetical protein		[72]

*Two names were assigned for the same effector [71,72].