Table 1.
Currently active companies working on miRNA-based diagnostics
| Companies | Product | Targeted miR | Disease type | Development phase | Reference |
|---|---|---|---|---|---|
| Interpace Diagnostics/Asuragen | ThyraMIR/ThyGENX | miR-29b-1-5p, miR-31-5p, miR-138-1-3p, miR-139-5p miR-146b-5p, miR-155, miR-204-5p, miR-222-3p, miR-375 and miR-551b-3p |
Thyroid and pancreatic cancer | Available | thygenext-thyramir.com |
| Rosetta Genomics/Precision Therapeutics Genoptix |
miRview mets Reveal |
miRNA library miRNA library |
Identify tumor origin of cancer Thyroid |
Available Available |
rosettagenomic.comoncotest.co.il genoptix.com |
| TAmiRNA TAmiRNA |
OsteomiR ThrombomiR |
Panel of 19 miRNAs Panel of 11 miRNAs |
Osteoporosis Cardiovasc. Disease |
Available Available |
tamirna.com - |
| Hummingbird Diagnostics | - | Panels (unknown) | Multiple (cancers, brain, heart) | Pre-Clinical & Phase 1 | hummingbird-diagnostics.com |
| DiamiR | CogniMIR Others |
Panel (unknown) Panel (unknown) |
Alzheimer Brain diseases |
Phase 1 | diamirbio.com |
| Mirnext | Panel with miR 423-5p | Heart failure | Development | hmirnext.com | |
| Quanterix/DestiNA Genomics | Simoa | miR-122 | Liver toxicity | Pre-Clinical | quanterix.com |