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. 2019 Jun 9;9(15):4354–4374. doi: 10.7150/thno.35125

Figure 11.

Figure 11

Anti-metastatic and pro-apoptotic effects of PEG-ss-aAPP/MTX micelles in vivo. (A) Area of superficial lung tumors, quantified with respect to untreated tumor-bearing control animals (defined as 100%). (B) Number of superficial lung tumors, quantified as in panel (A) (n = 5). (C) Representative sections of lung tissues stained with hematoxylin-eosin. Red arrows indicate tumors. Scale bar, 500 μm. (D) Staining of tumors collected on day 36 and stained to detect cells in early apoptosis (annexin V) or late apoptosis (propidium iodide, PI). (Magnification, 200) (E) Immunohistochemistry of tumor sections against p65.