AUC |
area under the curve |
CH
|
constant domain of heavy chain |
CL
|
constant domain of light chain |
CODV-Ig |
cross-over dual variable immunoglobulin |
Db-Ig |
diabody immunoglobulin |
DD |
dimerization domain |
DVD-Ig |
dual-variable domain immunoglobulin |
EHD2 |
IgE heavy chain domain 2 |
EGFR |
epidermal growth factor receptor |
Fab |
fragment antigen-binding |
Fc |
fragment crystallizable |
HER3 |
human epidermal growth factor receptor 3 |
hetEHD2 |
heterodimeric EHD2 |
HRG |
heregulin |
i.v. |
intravenous |
Ig |
immunoglobulin |
MHD2 |
IgM heavy chain domain 2 |
PDB |
protein data bank |
PK |
pharmacokinetic |
scFv |
single-chain fragment variable |
TNF |
tumor necrosis factor |
VH
|
variable domain of heavy chain |
VL
|
variable domain of light chain |