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. 2019 Jun 20;17:119–131. doi: 10.1016/j.isci.2019.06.026

Figure 1.

Figure 1

Global VDR Deletion Impairs Gut ILC3 Development in Mice

Colonic lamina propria (LP) cells were isolated from WT and VDR−/− mice, and the cells were analyzed by FACS for ILC3 populations.

(A–C) Representative FACS plots for analysis of RORγt+ILC3 (A), NKp46+ cells (B), and LTi4 and LTi0 cells (C) in WT and VDR−/− mice at steady state.

(D–F) Quantitation based on FACS data of RORγt+ILC3 (D), NKp46+ cells (E), and LTi4 and LTi0 cells (F) in WT and VDR−/− mice. The data were presented as percentage of the gated population and absolute cell number. **p < 0.01; ***p < 0.001. n = 4 each genotype. Data are represented as mean ± SEM.