Table 1.

Study inclusion and exclusion criteria

Inclusion criteria	Exclusion criteria
▪ 18 years of age or older	▪ Less than 18 years old
▪ Test HIV-1 negative (blood-based rapid HIV-1 test)	▪ Test HIV-1 positive (blood-based rapid HIV-1 test)
▪ Has been taking PrEP for at least 1 month prior to enrollment and planning to continue on PrEP	▪ Not currently taking PrEP
▪ Willing to be randomized to either clinic-based HIV-1 testing or at-home HIVST	▪ Unwilling to be randomized to either clinic-based testing or at-home HIVST
▪ Not currently enrolled in an HIV-1 prevention clinical trial	▪ Enrolled in an HIV-1 prevention clinical trial
	▪ Contraindication to use of tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) or TDF/lamivudine (TDF/3TC)
▪ Able and willing to provide written informed consent	▪ Unable or unwilling to provide written informed consent

Note that women who are pregnant or become pregnant during the study are still eligible for study participation

HIV-1 human immunodeficiency virus-1, HIVST HIV-1 self-testing, PrEP pre-exposure prophylaxis