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. 2019 Jul 5;35(14):i568–i576. doi: 10.1093/bioinformatics/btz365

Table 2.

Top 20 ranked genes along with their associated driver score and minimum P-value from IGAP (Lambert et al., 2013) and Jansen (Jansen et al., 2019) GWAS datasets

Genes Driver score Jansen P-value IGAP P-value
APOC1 42.92 <1E−308 <1E−308
APOE 41.75 <1E−308 <1E−308
BCAM 5.88 1.60E−143 4.66E−69
CD74 4.92 1.93E−02 1.20E−01
TREM2 4.65 2.95E−15 1.07E−03
CLPTM1 4.58 7.07E−50 2.80E−21
DEF6 4.28 5.94E−03 3.52E−02
SLC7A7 4.05 2.29E−03 2.36E−02
DOCK2 3.72 9.14E−04 4.82E−03
SPI1 3.62 1.06E−06 1.99E−06
STEAP3 3.61 3.63E−05 2.21E−02
PICALM 3.56 2.19E−18 1.91E−12
HMOX1 3.56 1.16E−02 1.43E−01
CLU 3.55 2.61E−19 2.48E−17
MS4A6A 3.55 1.55E−15 6.64E−11
IRF5 3.45 1.21E−02 1.48E−02
TYROBP 3.44 1.34E−02 5.40E−02
PARVG 3.42 1.44E−02 1.05E−03
ITGAL 3.41 1.92E−04 4.36E−03
PTPRC 3.33 2.12E−03 7.24E−03