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. Author manuscript; available in PMC: 2019 Jul 8.
Published in final edited form as: Ophthalmology. 2016 Oct 19;123(12):2537–2544. doi: 10.1016/j.ophtha.2016.09.001

Table 4.

Posterior means (and 95% credible intervals) for variance and covariance components estimated from a bivariate GLMM of choroidal thickness and modified Clinical Age-Related Maculopathy Staging (CARMS) category. Repeatability (R=Va+Vpe/(Va+Vpe+Ve)), heritability (H2= Va/(Va+Vpe+Ve) and genetic correlation between choroidal thickness and CARMS category (rA=Cov1,2/√(VA1*VA2) are shown where Va is genetic variance, Vpe is permanent environmental variance, Ve is the residual variance and Cov12 is the genetic covariance between traits.

Trait Genetic variance (VA) Permanent individual variance (Vpe) Residual variance (Ve) Heritability (H2) Genetic covariance (Cov1,2) Genetic correlation (rA)
Choroidal thickness 1540.85 (850.90–2273.01) 1479.79 (889.49–2031.82) 857.21 (769.19–951.88) 0.40 (0.24–0.56) −18.43 (−53.02-16.48) −0.18 (−0.49 - 0.16)
CARMS category 7.00 (3.01–11.12) 6.08 (2.77–9.26) 1 (fixed) 0.49 (0.26 – 0.72)