Table 4.
Posterior means (and 95% credible intervals) for variance and covariance components estimated from a bivariate GLMM of choroidal thickness and modified Clinical Age-Related Maculopathy Staging (CARMS) category. Repeatability (R=Va+Vpe/(Va+Vpe+Ve)), heritability (H2= Va/(Va+Vpe+Ve) and genetic correlation between choroidal thickness and CARMS category (rA=Cov1,2/√(VA1*VA2) are shown where Va is genetic variance, Vpe is permanent environmental variance, Ve is the residual variance and Cov12 is the genetic covariance between traits.
Trait | Genetic variance (VA) | Permanent individual variance (Vpe) | Residual variance (Ve) | Heritability (H2) | Genetic covariance (Cov1,2) | Genetic correlation (rA) |
---|---|---|---|---|---|---|
Choroidal thickness | 1540.85 (850.90–2273.01) | 1479.79 (889.49–2031.82) | 857.21 (769.19–951.88) | 0.40 (0.24–0.56) | −18.43 (−53.02-16.48) | −0.18 (−0.49 - 0.16) |
CARMS category | 7.00 (3.01–11.12) | 6.08 (2.77–9.26) | 1 (fixed) | 0.49 (0.26 – 0.72) |