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. 2019 Jul 5;294(27):10742. doi: 10.1074/jbc.W119.009748

Withdrawal: Reactive nitrogen species is required for the activation of the AMP-activated protein kinase by statin in vivo.

Hyoung Chul Choi, Ping Son, Zhonglin Xie, Yong Wu, Jian Xu, Miao Zhang, Yunzhou Dong, Shuangxi Wang, Kai Lau, Ming-Hui Zou
PMCID: PMC6615695  PMID: 31278161

VOLUME 283 (2008) PAGES 20186–20197

This article has been withdrawn by the authors. The LKB1 immunoblot from Fig. 1D was reused in Fig. 7D. The AMPK immunoblot from Fig. 2A was reused in Fig. 3A. Figs. 3C and 5 (A and B) contained splices. The authors state that the duplications of the blots occurred during the assembly of the paper. The undeclared splicings in Fig. 5 (A and B) were between the same immunoblots. The authors offered to published amended figures based upon those data and, alternatively, offered to repeat the experiments. However, the Journal declined both offers, a decision with which the authors respectfully disagree. Further, the results of this paper are confirmed by the results of complementary experiments presented in the manuscript, and the principal conclusion was further confirmed in publications from other laboratories (Ma, L. et al. (2012) PLoS One 7, e46055; Rossoni, L. V. et al. (2011) Clin. Sci. (Lond.) 121, 449–458; Dong, Q. et al. (2011) Int. J. Cardiol. 153, 311–316; and Chen, Z. et al. (2009) Circ. Res. 104, 496–505). The authors state that any errors in the construction of figures in the paper do not alter the scientific conclusions of the work, and they stand by the conclusions of the paper.


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