Skip to main content
. 2019 Jun 6;8(6):547. doi: 10.3390/cells8060547

Figure 10.

Figure 10

The effect of a specific IL-1 receptor antagonist (IL1RA) administrated to CAL65 anaplastic thyroid cancer cells for 3 h alone (A) or in combination with IL-1β (B,C) on (A) phospho-TAK1 (p-TAK1) (measured in the cell lysates) and P65 NF-kB (measured in the nuclear extracts) by ELISA; (B) Glyoxalase 1 (Glo1)-specific activity, measured by a spectrophotometric assay; and (C) migration and invasion capabilities, evaluated by specific assays. (D) Effect of the long-term exposure (2 weeks) of TPC1 papillary thyroid cancer cells to IL-1β on Glo1 specific activity (s.a.), migration, and invasion. Histograms indicate mean ± SD of three different cultures each tested in triplicate. * p < 0.05, ** p < 0.01, and *** p < 0.001 compared to untreated cells.