Table 1:
Demographics of entire cohort, patients with good and poor collaterals and p-value for difference between Tan collateral status arms.
| Entire cohort (n=130) | Good collaterals (n=97) | Poor collaterals (n=33) | p-value | |
|---|---|---|---|---|
| Age | 71 (60–80) | 71 (59–78) | 73 (60–82) | 0.425 |
| Female | 63 (49) | 51 (53) | 12 (36) | 0.107 |
| Ethnicity Hispanic | 11 (9) | 4 (4) | 7 (21) | 0.006 |
| Race White | 111 (85) | 83 (86) | 28 (85) | 1.0 |
| Hypertension | 104 (80) | 78 (80) | 26 (79) | 0.840 |
| Hyperlipidemia | 63 (48) | 45 (46) | 18 (55) | 0.418 |
| Atrial fibrillation | 49 (38) | 38 (39) | 11 (33) | 0.550 |
| Diabetes | 38 (29) | 32 (33) | 6 (18) | 0.095 |
| Prior CVA | 21 (16) | 15 (15) | 6 (18) | 0.714 |
| Presentation NIHSS | 16 (12–21) | 16 (12–20) | 18 (11–21) | 0.592 |
| Treated with tPA | 8 (6) | 5 (5) | 3 (9) | 0.679 |
| MCA occlusion | 82 (63) | 58 (60) | 24 (73) | 0.184 |
| Ischemic core (mL) | 9.8 (1.7–23.4) | 7.8 (0–17.3) | 21.7 (6.1–42.9) | 0.001 |
| Perfusion lesion (mL) | 117.1 (76.3–162.3) | 110.5 (65.5–157.0) | 138.4 (108.1–181.5) | 0.008 |
| Mismatch volume (mL) | 104.8 (62.7–138.8) | 90.9 (60.0–139.5) | 108.1 (87.4–136.4) | 0.164 |
| Hypoperfusion intensity ratio | 0.35 (0.21–0.53) | 0.28 (0.15–0.49) | 0.44 (0.26–0.58) | <0.001 |
| Time from last known well to baseline imaging | 10:15 (8:20–11:47) | 10:16 (8:12–11:47) | 9:46 (8:32–11:36) | 0.900 |
| Time from last known well to femoral puncture | 11:35 (9:47–12:59) | 11:28 (9:37–13:03) | 11:48 (10:22–12:53) | 0.610 |
| Time from last known well to reperfusion | 12:34 (17:57–13:42) | 12:23 (9:48–13:42) | 12:39 (11:30–13:41) | 0.465 |
| ASPECTS | 8 (7–9) | 8 (7–9) | 8 (7–9) | 0.975 |
| Right hemisphere stroke | 60 (46) | 45 (46) | 15 (45) | 0.926 |
| Baseline SBP | 146 (134–161) | 147 (135–160) | 143 (128–160) | 0.487 |
| Creatinine | 0.9 (0.78–1.11) | 0.9 (0.78–1.1) | 0.9 (0.78–1.2) | 0.395 |
| Glucose | 124 (108–152) | 125 (108–151) | 124 (109–155) | 0.634 |
| WBC | 8.9 (6.9–10.9) | 9.2 (6.98–11.0) | 7.9 (6.9–10.4) | 0.394 |
| Platelets | 231 (170–262) | 215 (168–265) | 209 (174–240) | 0.385 |
| Hematocrit | 40.8 (36.9–43.3) | 40.4 (36.2–43.2) | 41 (39.7–44) | 0.148 |
| INR | 1.04 (1.0–1.11) | 1.0 (1.0–1.1) | 1.1 (1.0–1.2) | 0.051 |
Notes:
1) Ethnicity: N=96 & 33; Perfusion lesion: N=96 & 33; Time from stroke onset to femoral puncture: N=49 &16; Time from stroke onset to reperfusion: N=45 & 14; ASPECTS: N=86 &31; HIR: N=96 & 33.
2) Ischemic core = relative cerebral blood flow <30%; perfusion lesion = Tmax <6 seconds; mismatch volume = perfusion lesion-ischemic core.
3) Continuous variables: median (IQR); categorical data: n(%).