Table 2:

Selected outcomes in DEFUSE 3 for the entire cohort, patients with good and poor collaterals and p-value for difference between Tan collateral status arms.

	Entire cohort (n=130)	Good collaterals (n=97)	Poor collaterals (n=33)	p-value
Early neurologic deterioration	13 (10)	12 (12)	1 (3)	0.182
Ischemic core volume (mL) at 24 hours	39.3 (23.9–107.1)	32.9 (17.5–68.7)	65.7 (36.2–164.5)	0.002
Ischemic core growth (mL) from baseline to 24 hours	29.7 (13.2–74.9)	26.9 (13.1–54.5)	43.1 (13.6–131.3)	0.031
Perfusion lesion (mL) at 24 hours	6.8 (0–63.5)	4.4 (0–47.4)	29.8 (0–76.8)	0.071
Mismatch volume (mL) at 24 hours	−26.2 (−59.3 - −2.5)	−26.4 (−54.6 - −4.6)	−36.2 (−126.8 - −0.7)	0.139
Endovascular therapy randomization	65 (50)	49 (51)	16 (48)	0.840
Reperfusion >90%*	47 (48)	38 (51)	9 (39)	0.333
Complete recanalization on CTA/MRA	56 (50)	44 (52)	12 (43)	0.414
Reperfusion and/or recanalization	54 (47)	42 (48)	12 (41)	0.519
Symptomatic ICH	6 (5)	5 (5)	1 (3)	0.693
Parenchymal hematoma 2 (ECASS II)	8 (6)	6 (6)	2 (6)	1.0
mRS 0–2 at 90 days	42 (32)	29 (30)	13 (39)	0.314
Stroke-related death at 90 days	26 (20)	18 (19)	8 (24)	0.481

Notes:

1) Ischemic core volume at 24 hours: N=96 & 33; Ischemic core growth: N=96 & 33; reperfusion: N=75 & 23; recanalization: N=85 & 28; reperfusion and/or recanalization: N=87 & 29.

2) Continuous variables: median (IQR); categorical data: n(%).