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. 2019 Apr 11;7(2):28. doi: 10.3390/biomedicines7020028

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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rbm24a morphants are visually impaired and unable to respond to OMR. (A) OMR analysis of control (n = 19), rbm24a AUG MO at 1.0–1.2 ng (n = 18), and rbm24a AUG MO at 2.0–2.5 ng (n = 10) larvae plotted as a bar graph which shows the shifts in the population between the initial and final positions (Bowker’s test of symmetry p-value *** = 0.0004; Wilcoxon–Mann–Whitney p-value * = 0.0094); (B) Individual analysis of rbm24a morphant compared to wild type; (C) individual analysis of rbm24a morphant compared to mbl^−/−. In contrast to wild type fish, rbm24a morphant fish do not align with the OMR, indicating a visual defect. n.s., not significant.