The pH-responsive release of Fe2+ from the surface coated ATA-IONPs.
(a) Quantitative analysis of the Fe2+ released from ATA-IONPs at different pH environments, (data represents the mean ± standard error of the mean of three independent experiments) and (b) the corresponding representative TEM images of ATA-IONPs in 1xPBS buffer at different pH values 7.4, 6.0, and 5.0. The diameter of the ATA-IONPs was estimated from 50 particles each which are free from the aggregated state. Data represent the mean ± standard error of the diameter of 50 particles each. (c) Hydrodynamic size of NPs at respective pH.