Skip to main content
. 2019 Jun 6;10(7):1068–1081. doi: 10.1039/c9md00018f

Table 2. Albumin-binding peptide ligands.

Cargo
Albumin-binding molecule Conjugate
Factor Ref.
Type τ 1/2 Affinity τ 1/2
Anti-HER2§ 4.3 h (i.v.)a 89D03 (15b nM) n.a. Single copy: 31.2 h (i.v.)a 7a 65
Double copy: 84.5 h (i.v.)a 20a
huPA inhibitor 18 min (i.v.)c F-tag (39b, 220c, 320d nM) 168b, 780c nM 7.4 h (i.v.)c 25c 62
hFXIIa inhibitor 13 min (i.v.)d 224a, 1600d nM 5.2 h (i.v.)d 24d
Fab§ 53 min (i.v.)d SA21 (467b, 266c, 320d, 7e nM) 320d nM 32.4 h (i.v.)d 37d 60
24 min (i.v.)e 10.4 h (i.v.)e 26e
huPA inhibitor 30 min (i.v.)e 354b, 14e nM 24 h (i.v.)e 48e 67
Exendin-4 30 min (i.v.)c 610a, 1560b, 210c nM 2 d (i.v.)a 22c 83
11 h (i.v.)c