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. 2010 Feb 23;33(2):72–76. doi: 10.1002/clc.20692

Correlation Study of Pulmonary Embolism and High‐density Lipoprotein Cholesterol

YuPeng Wang 1, Ping Wang 1, HongWei Li 1,
PMCID: PMC6652962  PMID: 20186986

Abstract

Background

It is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high‐density lipoprotein cholesterol.

Hypothesis

Pulmonary embolism has a negative correlation with the level of high‐density lipoprotein cholesterol.

Methods

A total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non‐trunk embolism in group B.

Results

The results showed that the level of high‐density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non‐trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high‐density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C‐reactive protein.

Conclusions

Pulmonary arterial trunk embolism is negatively correlated with the level of high‐density lipoprotein cholesterol. Copyright © 2010 Wiley Periodicals, Inc.

Full Text

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