Abstract
Background
Recent studies have demonstrated that statins may possess anti‐arrhythmic properties in addition to their lipid‐lowering effects.
Methods
Studies which reported the association of statins with the incidence of ventricular arrhythmias were identified through a systematic review of the published literature.
Results
Statins have been associated with a significant reductions in ventricular arrhythmia in cardiomyopathy patients with an implantable cardioverter defibrillator, although randomized trials have not been completed.
Conclusions
Published data suggests that statins may possess anti‐arrhythmic properties that reduce the propensity for ventricular arrhythmias. Most of this data is observational; more randomized, placebo‐controlled trials are needed. Copyright © 2009 Wiley Periodicals, Inc.
Full Text
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