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. 2007 Apr 18;30(4):200–203. doi: 10.1002/clc.9

A case report of simultaneous thrombosis of two coronary artery stents in association with clopidogrel resistance

Jin Sun Lee 1,, Steven P Dunn 2, Helen M Marshall 3, Mauricio G Cohen 4, Susan S Smyth 5
PMCID: PMC6653341  PMID: 17443655

Abstract

Despite aggressive antiplatelet therapy in the setting of PCI, the incidence of acute stent thrombosis remains approximately 0.5–2%. We report a patient with simultaneous thrombosis of two drug‐eluting coronary artery stents, suggesting a systemic thrombotic state. Evaluation by optical platelet aggregometry revealed clopidogrel resistance, which was overcome at a higher drug dose. We aim to highlight the potential utility of platelet function analysis to guide therapy for patients in whom inadequate antiplatelet therapy may have catastrophic clinical outcomes. Copyright © 2007 Wiley Periodicals, Inc.

Keywords: platelet, thrombosis, angiography, stent

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