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. 2009 Apr 20;32(6):E94–E96. doi: 10.1002/clc.20291

Paclitaxel‐induced ST‐Segment Elevations

Gökmen Gemici 1,, Altuǧ Çinçin 2, Muzaffer Deǧertekin 1, Ahmet Oktay 2
PMCID: PMC6653473  PMID: 19382279

Abstract

A 51‐year‐old woman presented with severe chest pain minutes after starting intravenous paclitaxel as a part of the systemic chemotherapy due to ovarian carcinoma. The electrocardiogram (ECG) revealed sinus rhythm with ST‐segment elevations in inferior and anterior leads. The ST‐segment elevations resolved immediately after sublingual nitroglycerine. Cardiac troponin T and CPK MB levels remained in the normal range at repeat measurements. It was presumed that in spite of standard premedication, paclitaxel had induced acute coronary syndrome with ST‐segment elevations in this patient. Copyright © 2009 Wiley Periodicals, Inc.

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