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. 2008 Aug 25;31(8):360–367. doi: 10.1002/clc.20241

Simultaneous Doppler Tracing of the Mitral Inflow and Annular Motion Provides a Useful Means of Evaluating Left Ventricular Diastolic Function

Jin‐Oh Choi 1, Seung Woo Park 1,✉, Dae‐Hee Shin 1, Hyejin Han 1, Sungwon Cho 1, Jun Hyung Kim 1, Young Bin Song 1, Sang‐Chol Lee 1
PMCID: PMC6653532  PMID: 18727000

Abstract

Background

In this study, we evaluated the feasibility and clinical usefulness of TS E−E ′, the time interval between the onsets of early diastolic mitral inflow velocity (E) and mitral annular velocity (E′), obtained by simultaneously tracing E and E′, in terms of evaluating diastolic function.

Methods

By the diastolic functional status, 105 patients were allocated to abnormal relaxation, pseudonormal filling (PN), or normal diastolic function groups (n = 30, 43, and 32, respectively). The TS E−E ′ was measured in the same cardiac cycle by the pulsed‐wave Doppler (PWD) tracing of mitral inflow near the septal annulus with appropriate filter and gain settings.

Results

TS E−E ′ was prolonged in the PN group versus the normal group (34.1 ± 12.2 msec versus 12.1 ± 8.5 msec, p≤0.001). The area under the receiver operating characteristic curve of TS E−E ′ for the detection of PN was 0.91 (95% confidence interval [CI]; 0.85 ∼ 0.97, p<0.001), and 24.0 msec was determined to be the optimal cut‐off value (specificity 83.7%, sensitivity 90.3%).

Conclusion

Simultaneous measurement of TS E−E ′ is feasible and clinically applicable for the grading of diastolic dysfunction (DD). Copyright © 2008 Wiley Periodicals, Inc.

Keywords: diastole, pulsed Doppler echocardiography, cardiac function

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